Men's wildcards for Miami have gone to James Blake, Milos Raonic, Ryan Harrison, Jack Sock and Bernard Tomic.
Blake is the only veteran in the group, his ranking falling after injuries caused him to miss most of the second half of last year.
Women's wildcards were awarded to Dinara Safina, Sorana Cirstea, Sabine Lisicki, Heather Watson, Coco Vandeweghe and Madison Keys.
Former world No. 1 Safina has won just one match in four tournaments so far during the year, though she managed to win the doubles in Kuala Lumpur last week. The Russian is struggling to find her form after being plagued with back troubles for the last 18 months.
Cirstea defeated Lisicki in three sets in Indian Wells qualifying this week.