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WATCH: Roger Federer speaks about his future after a disappointing Wimbledon defeat.

Coco Gauff revealed on Instagram that she tested positive for COVID-19 and will not be able to play in the 2021 Tokyo Olympics. She is the latest in a slew of withdrawals including most recently Roger Federer and Matteo Berrettini.

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Rafael Nadal and Serena Williams previously announced that they wouldn't compete in this summer's Olympic Games in Tokyo, and Novak Djokovic said he is "50-50," given the coronavirus restrictions that will be imposed on athletes in Japan.

Roger Federer will not be among those athletes, as the 39-year-old announced on Tuesday that he wouldn't be competing after experiencing a setback to his knee at Wimbledon.

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Federer rarely looked like his comfortable self at the All England Club. He narrowly emerged from his first-round match against Adrian Mannarino when the Frenchman was forced to retire, and after wins over Richard Gasquet, Cameron Norrie and Lorenzo Sonego, the Swiss lost to Hubert Hurkacz in the quarterfinals, 6-3, 7-6 (4), 6-0. He had never lost a set at Wimbledon by that margin.

"I'm going to take a couple of days and sit down," said Federer when asked about his Olympic participation following the loss. "I'm sorry if I'm repetitive. I said everything waits till Wimbledon is done. Wimbledon is done now. I haven't taken a decision yet where we go from here.

"Yeah, I can't tell you anything more than that. I will sit down and hopefully make an announcement rather sooner than later, of course, also for me and everybody, my family and team, so forth."

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I am greatly disappointed, as it has been an honor and highlight of my career each time I have represented Switzerland. I have already begun rehabilitation in the hopes of returning to the tour later this summer. Roger Federer

Federer's health has been his primary focus as he approaches his 40th birthday, so much that he withdrew from Roland Garros after winning his first three matches. He is 9-4 this season, but has only played 19 matches since the end of 2019.

At the Olympics, Federer has done all but win singles gold. He finished second to Andy Murray (at Wimbledon) in 2012, and in his Olympic debut at the 2000 Athens Games played for a bronze medal, losing to Arnaud Di Pasquale. At the 2008 Summer Games in Beijing, he won doubles gold with Stan Wawrinka.

On Monday, Canada's Bianca Andreescu also wrote on social media that she wouldn't play in Tokyo, due to "all the challenges we are facing as it relates to the pandemic."

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We will continue to update this story.