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John Isner has become the first man in the Open Era to win 500 career tie-breaks, getting his milestone 500th in the first set of his 7-6 (8), 7-5 victory over Emilio Gomez in the quarterfinals of Dallas.

"I'm very glad I didn't have to win 501," said Isner, who got the very first break of the match in the very last game of the match.

MOST TIE-BREAKS WON IN OPEN ERA (men):
500: John Isner [500-319]
466: Roger Federer [466-247]
398: Ivo Karlovic [398-403]
328: Pete Sampras [328-194]
325: Feliciano Lopez [325-278]

In terms of career winning percentage in tie-breaks, Isner’s .611 ranks at No. 11 in the Open Era. Not surprisingly, the Top 2 are from the Big 3: Federer at .654 and Novak Djokovic at .651. Rafael Nadal comes in just behind Isner at No. 12, with .610.

Up next for Isner in the semifinals will be fellow American J.J. Wolf, who took out another American, Frances Tiafoe, in the first quarterfinal match of the day, 4-6, 6-3, 6-4. Wolf's win over the No. 14-ranked Tiafoe was the biggest win of his career.