Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2006 |
Miami Open
|
Championship | Sebastien Grosjean |
3-6
6-7 |
| 2005 |
Mutua Madrilena Masters Madrid
|
Championship | Sebastien Grosjean |
5-7
6-4 2-6 |
| 2004 |
Summer Olympics
|
Championship | Sebastien Grosjean |
6-7
6-4 6-0 |
| 2004 |
Campionati Internazionali d'Italia
|
Championship | Sebastien Grosjean |
5-7
2-6 |
| year | Event | RND | Winner | Results |
|---|
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| 2020 |
Rolex Paris Masters
|
1/16 | Rafael Nadal |
4-6
7-6 6-4 |
| 2020 |
Rolex Paris Masters
|
1/32 | Feliciano Lopez |
6-7
1-6 |
