Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2012 |
Family Circle Cup
United States, South Carolina, Charleston |
1/32 | Galina Voskoboeva |
3-4
|
| 2012 |
Sony Ericsson Open
United States, Florida, Miami |
1/64 | Ekaterina Makarova |
6-1
7-5 |
