Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2016 |
Mercedes Cup
|
1/16 | Mikhail Youzhny |
7-6
6-3 |
| 2014 |
Shanghai Rolex Masters
|
Quarter Finals | Feliciano Lopez |
7-5
4-6 4-6 |
| 2014 |
Mutua Madrid Open
|
1/16 | Feliciano Lopez |
6-3
3-6 4-6 |
| 2011 |
China Open
China, Beijing |
Championship | Mikhail Youzhny |
7-6
2-6 5-7 |
| 2009 |
Sunrise
|
Championship | Feliciano Lopez |
2-6
3-6 |
| 2004 |
Dubai Duty Free Tennis Championships
|
Championship | Feliciano Lopez |
6-4
4-6 6-4 |
| 2003 |
BNP Paribas Masters
|
Championship | Feliciano Lopez |
6-7
3-6 |
| 2003 |
Wimbledon
|
Championship | Feliciano Lopez |
7-6
6-3 6-2 |
| 2002 |
Tashkent
|
Championship | Mikhail Youzhny |
7-6
6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Andalucia Open
|
1/16 | Feliciano Lopez |
6-4
6-4 |
| 2021 |
Miami Open
|
1/64 | Alexei Popyrin |
4-6
6-7 |
| 2021 |
Mexican Open
|
1/16 | Miomir Kecmanovic |
6-4
6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2018 |
St. Petersburg Open
|
1/8 | Roberto Bautista Agut |
6-7
6-3 3-6 |
| 2018 |
St. Petersburg Open
|
1/16 | Mikhail Youzhny |
6-7
4-6 |
| 2018 |
US Open ATP
|
1/64 | Marcos Baghdatis |
6-4
6-4 2-6 3-1 |
| 2018 |
Rogers Cup
|
1/16 | Robin Haase |
5-7
2-6 |
