Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2016 |
Erste Bank Open
Austria, Vienna |
1/8 | John Isner |
7-6
3-6 7-6 |
| 2016 |
Australian Open
|
1/16 | John Isner |
7-6
6-7 2-6 4-6 |
| 2015 |
AEGON Championships
|
1/8 | John Isner |
7-6
6-7 7-6 |
| 2014 |
Shanghai Rolex Masters
|
1/8 | Feliciano Lopez |
3-6
4-6 |
| 2014 |
Wimbledon
|
1/16 | Feliciano Lopez |
6-7
7-6 7-6 7-5 |
| 2012 |
US Men's Clay Court Championships
|
Semi Finals | John Isner |
7-6
6-7 3-6 |
| 2012 |
Australian Open
Australia, Victoria, Melbourne |
1/16 | Feliciano Lopez |
3-6
7-6 4-6 7-6 1-6 |
| 2011 |
BNP Paribas Masters
|
Championship | John Isner |
6-4
6-2 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Delray Beach Open
|
Quarter Finals | Sebastian Korda |
6-3
4-6 6-3 |
| 2021 |
Delray Beach Open
|
1/8 | John Isner |
4-6
6-7 |
| 2020 |
Roland Garros ATP
|
1/32 | Sebastian Korda |
6-4
6-4 2-6 6-4 |
| 2020 |
US Open ATP
|
1/64 | Steve Johnson |
6-7
6-3 6-7 6-3 7-6 |
