Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| 2020 |
Rolex Paris Masters
|
1/16 | Rafael Nadal |
4-6
7-6 6-4 |
| 2020 |
Rolex Paris Masters
|
1/32 | Feliciano Lopez |
6-7
1-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2018 |
Tianjin Open, Qualification
|
1/12 (Special Qual) | Sabine Lisicki |
6-2
6-1 |
| 2018 |
Tashkent Open
|
1/16 | Vera Lapko |
1-6
3-6 |
| 2018 |
US Open, Qualification WTA
|
1/32 | Anastasia Potapova |
6-7
3-6 |
| 2018 |
US Open, Qualification WTA
|
1/64 | Bojana Jovanovski |
6-4
6-4 |
