Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2012 |
Open Sud de France
France, Montpellier |
1/8 | Guillaume Rufin |
6-7
3-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Andalucia Open
|
1/16 | Feliciano Lopez |
6-4
6-4 |
| 2021 |
Miami Open
|
1/64 | Alexei Popyrin |
4-6
6-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2015 |
Roland Garros, Qualification
|
1/64 | Thomas Fabbiano |
6-4
6-2 |
| 2015 |
Bordeaux
|
1/16 | Jared Donaldson |
4-6
4-6 |
| 2015 |
Bordeaux, Qualification
|
Quarter Finals | Guillaume Rufin |
6-1
6-3 |
| 2015 |
Bordeaux, Qualification
|
1/8 | Guillaume Rufin |
7-6
3-6 5-7 |
