Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2014 |
Sony Open Tennis
United States, Florida, Miami |
1/32 | Feliciano Lopez |
2-6
6-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Open Sud de France
|
1/8 | Peter Gojowczyk |
7-6
6-7 3-6 |
| 2021 |
Open Sud de France
|
1/16 | Jiri Vesely |
1-6
1-6 |
| 2021 |
Australian Open ATP
|
1/32 | Pablo Carreno Busta |
3-6
6-7 6-2 4-6 |
| 2021 |
Australian Open ATP
|
1/64 | Jiri Vesely |
4-6
6-3 7-6 3-6 3-6 |
| 2021 |
Murray River Open
|
Quarter Finals | Felix Auger-Aliassime |
6-7
0-0 |
| 2021 |
Murray River Open
|
1/8 | Jiri Vesely |
6-4
6-2 |
| 2021 |
Murray River Open
|
1/16 | Jiri Vesely |
7-5
6-7 3-6 |
| 2021 |
Murray River Open
|
1/32 | Jiri Vesely |
4-6
4-6 |
