Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| 2020 |
Rolex Paris Masters
|
1/16 | Rafael Nadal |
4-6
7-6 6-4 |
| 2020 |
Rolex Paris Masters
|
1/32 | Feliciano Lopez |
6-7
1-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open WTA
|
1/32 | Yulia Putintseva |
6-4
1-6 6-2 |
| 2021 |
Yarra Valley Classic
|
1/16 | Garbine Muguruza |
6-2
6-0 |
| 2021 |
Yarra Valley Classic
|
1/32 | Alison van Uytvanck |
2-6
0-6 |
| 2020 |
Roland Garros WTA
|
1/32 | Irina Bara |
6-1
4-0 |
| 2020 |
Roland Garros WTA
|
1/64 | Alison van Uytvanck |
2-6
6-3 6-1 |
