The stage was set for a historic moment; the match happened in the second round.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2008 |
Australian Open WTA
Australia, Victoria, Melbourne |
Championship | Serena Williams |
3-6
4-6 |
| 2007 |
Kremlin Cup
Russia, Moscow |
Championship | Serena Williams |
6-4
7-6 |
| 2007 |
Sony Ericsson Open
United States, Florida, Miami |
Championship | Serena Williams |
6-1
6-4 |
| 2007 |
Australian Open WTA
Australia, Victoria, Melbourne |
Championship | Serena Williams |
7-6
6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2015 |
Tianjin Open
|
1/16 | Ying-Ying Duan |
3-6
3-6 |
| 2015 |
Tianjin Open, Qualification
|
Quarter Finals | Nicole Vaidisova |
6-1
5-7 6-4 |
| 2015 |
Tianjin Open, Qualification
|
1/8 | Nicole Vaidisova |
4-6
1-6 |
| 2015 |
Tianjin Open, Qualification
|
1/16 | Nicole Vaidisova |
6-3
2-6 0-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2020 |
Roland Garros WTA
|
1/32 | Tsvetana Pironkova | |
| 2020 |
Roland Garros WTA
|
1/64 | Serena Williams |
6-7
0-6 |
| 2020 |
US Open WTA
|
Semi Finals | Victoria Azarenka |
6-1
3-6 3-6 |
| 2020 |
US Open WTA
|
Quarter Finals | Serena Williams |
6-4
3-6 2-6 |
| 2020 |
US Open WTA
|
1/8 | Serena Williams |
3-6
7-6 3-6 |
| 2020 |
US Open WTA
|
1/16 | Serena Williams |
6-2
2-6 2-6 |
| 2020 |
US Open WTA
|
1/32 | Serena Williams |
2-6
4-6 |
| 2020 |
US Open WTA
|
1/64 | Serena Williams |
5-7
3-6 |
| 2020 |
Western & Southern Open
|
1/8 | Maria Sakkari |
5-7
7-6 6-1 |
| 2020 |
Western & Southern Open
|
1/16 | Serena Williams |
6-7
6-3 6-7 |
