Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2011 |
Australian Open WTA
Australia, Victoria, Melbourne |
Championship | Nadia Petrova |
6-4
6-1 |
| 2011 |
Australian Open WTA
Australia, Victoria, Melbourne |
Championship | Alicia Molik |
1-6
6-3 8-6 |
| 2011 |
Moorilla Hobart International
Australia, Hobart |
Championship | Sara Errani |
6-1
6-0 |
| 2011 |
Moorilla Hobart International
Australia, Hobart |
Championship | Alicia Molik |
7-5
6-3 |
| 2010 |
Bell Challenge
Canada, Quebec, Quebec City |
Championship | Anna Tatishvili |
6-3
2-6 2-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Yannick Hanfmann |
5-7
2-6 |
| 2021 |
Mexican Open
|
1/16 | Laslo Djere |
2-6
3-6 |
