Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2016 |
Brisbane International
|
1/16 | Viktor Troicki |
7-6
6-1 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Dubai Tennis Championships, Qualification
|
1/6 (Special Qual) | Emil Ruusuvuori |
6-2
6-2 |
| 2021 |
Dubai Tennis Championships, Qualification
|
1/12 (Special Qual) | Viktor Troicki |
7-5
6-0 |
| 2021 |
Open 13 Provence, Qualification
|
1/8 | Steven Diez |
6-3
2-6 2-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Yannick Hanfmann |
5-7
2-6 |
| 2021 |
Mexican Open
|
1/16 | Laslo Djere |
2-6
3-6 |
