Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Lugano
|
1/16 | Hiroki Moriya |
1-6
6-3 7-5 |
| 2021 |
Biella 4
|
Final | Daniel Masur |
6-3
6-7 7-5 |
| 2021 |
Biella 4
|
Semi Finals | Matthias Bachinger |
7-5
6-4 |
| 2021 |
Biella 4
|
Quarter Finals | Matthias Bachinger |
6-7
0-1 |
| 2021 |
Biella 4
|
1/8 | Matthias Bachinger |
6-3
7-5 |
| 2021 |
Biella 4
|
1/16 | Matthias Bachinger |
7-6
2-6 6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Andalucia Open
|
1/16 | Feliciano Lopez |
6-4
6-4 |
| 2021 |
Miami Open
|
1/64 | Alexei Popyrin |
4-6
6-7 |
| 2021 |
Mexican Open
|
1/16 | Miomir Kecmanovic |
6-4
6-4 |
