Muguruza was fresh off a runner-up finish at the Qatar Total Open over the weekend.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/32 | Alex de Minaur |
3-6
3-6 5-7 |
| 2021 |
Australian Open ATP
|
1/64 | Pablo Cuevas |
6-4
4-6 6-2 6-2 |
| 2021 |
Great Ocean Road Open
|
1/8 | Hubert Hurkacz |
7-5
7-5 |
| 2021 |
Great Ocean Road Open
|
1/16 | Pablo Cuevas |
5-7
3-6 |
| 2021 |
Great Ocean Road Open
|
1/32 | Pablo Cuevas |
6-4
6-2 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Anna Kalinskaya |
6-4
7-6 |
| 2021 |
Dubai Duty Free Tennis Championships
|
1/32 | Garbine Muguruza |
3-6
5-7 |
| 2021 |
Dubai Duty Free Tennis Championships, Qualification
|
1/8 | Irina-Camelia Begu |
6-0
4-0 |
| 2021 |
Dubai Duty Free Tennis Championships, Qualification
|
1/16 | Irina-Camelia Begu |
7-6
4-6 6-0 |
