Kvitova and Muguruza were playing in Charleston for the first time since 2018 and 2013.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Volvo Car Open
|
1/8 | Danka Kovinic |
6-4
6-1 |
| 2021 |
Volvo Car Open
|
1/16 | Petra Kvitova |
6-7
2-6 |
| 2021 |
Miami Open
|
1/8 | Elina Svitolina |
6-2
5-7 5-7 |
| 2021 |
Miami Open
|
1/16 | Petra Kvitova |
6-1
6-2 |
| 2021 |
Miami Open
|
1/32 | Petra Kvitova |
6-0
6-4 |
| 2021 |
Dubai Duty Free Tennis Championships
|
1/16 | Jil Teichmann |
2-6
4-3 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Billie Jean King Cup Playoffs
|
Championship | Xiyu Wang |
1-6
6-3 2-6 |
| 2021 |
Copa Colsanitas
|
1/16 | Arantxa Rus |
4-6
7-5 4-6 |
| 2021 |
Miami Open
|
1/32 | Maria Sakkari |
6-2
6-3 |
| 2021 |
Miami Open
|
1/64 | Arantxa Rus |
3-6
2-6 |
