Lopez, playing his record 75th successive Grand Slam, has won a five-setter in 21 of them.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| 2016 |
Internazionali BNL d'Italia
|
1/32 | Kevin Anderson |
6-4
7-6 |
| 2013 |
Apia International Sydney
Australia, Sydney |
1/8 | Kevin Anderson |
6-3
6-4 |
| 2012 |
AEGON Championships
|
1/8 | Kevin Anderson |
7-6
7-6 |
| 2011 |
Brisbane International
Australia, Brisbane |
Championship | Kevin Anderson |
3-6
1-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/64 | Matteo Berrettini |
6-7
5-7 3-6 |
| 2021 |
Great Ocean Road Open
|
1/8 | Karen Khachanov |
3-6
6-7 |
| 2021 |
Great Ocean Road Open
|
1/16 | Kevin Anderson |
6-4
6-2 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
| 2020 |
Rolex Paris Masters
|
1/16 | Daniil Medvedev |
6-6
|
| 2020 |
Rolex Paris Masters
|
1/32 | Kevin Anderson |
2-5
|
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Australian Open ATP
|
1/16 | Andrey Rublev |
7-5
6-2 6-3 |
| 2021 |
Australian Open ATP
|
1/32 | Feliciano Lopez |
5-7
3-6 6-3 7-5 6-4 |
| 2021 |
Great Ocean Road Open
|
1/32 | Kevin Anderson |
4-6
5-7 |
