Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2018 |
Taiwan Open
|
1/8 | Yulia Putintseva |
6-3
7-6 |
| 2018 |
Taiwan Open
|
1/16 | Kai-Chen Chang |
5-7
2-6 |
| 2017 |
Prudential Hong Kong Tennis Open
|
1/16 | Wang Qiang |
3-6
0-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Biella 4
|
1/16 | Andreas Seppi |
6-4
3-6 3-6 |
