Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Orlando
|
1/8 | Jack Sock |
3-6
4-6 |
| 2021 |
Biella 4
|
1/16 | Andreas Seppi |
6-4
3-6 3-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2016 |
Indian Wells Masters, Qualification
|
1/24 (Special Qual) | Radek Stepanek |
5-7
6-0 1-6 |
