Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Orlando
|
Quarter Finals | Christian Harrison |
6-7
3-6 |
| 2021 |
Orlando
|
1/8 | Jack Sock |
3-6
4-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2019 |
Seville
|
1/32 | Inigo Cervantes |
3-6
0-6 |
| 2019 |
Mallorca
|
1/32 | Matteo Viola |
2-6
2-6 |
| 2019 |
Segovia
|
1/32 | Frederico Gil |
6-7
4-6 |
