Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2019 |
Lyon Open
|
Championship | ||
| 2018 |
Rakuten Japan Open Tennis Championships
|
1/16 | Martin Klizan |
6-4
7-6 |
| 2016 |
Shanghai Masters
China, Shanghai |
1/32 | Steve Johnson |
6-4
6-3 |
| 2015 |
Valencia Open 500
|
1/16 | Steve Johnson |
6-3
6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Monte Carlo Masters, Qualification
|
1/14 (Special Qual) | Salvatore Caruso |
3-6
4-6 |
| 2021 |
Marbella
|
Quarter Finals | Alessandro Giannessi |
0-6
3-6 |
| 2021 |
Marbella
|
1/8 | Martin Klizan |
3-6
3-6 |
| 2021 |
Marbella
|
1/16 | Martin Klizan |
1-6
6-7 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Yannick Hanfmann |
5-7
2-6 |
| 2021 |
Mexican Open
|
1/16 | Laslo Djere |
2-6
3-6 |
