Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2018 |
Miami Open
|
1/16 | Borna Coric |
5-7
7-6 6-3 |
| 2016 |
Davis Cup 1/4 finals
|
Championship | Borna Coric |
4-6
6-3 3-6 4-6 |
| 2015 |
Roland Garros
|
1/16 | Jack Sock |
6-2
6-1 6-4 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Rotterdam Open
|
Semi Finals | Marton Fucsovics |
4-6
1-6 |
| 2021 |
Rotterdam Open
|
Quarter Finals | Borna Coric |
7-6
7-6 |
| 2021 |
Rotterdam Open
|
1/8 | Borna Coric |
3-6
2-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Biella 4
|
1/16 | Andreas Seppi |
6-4
3-6 3-6 |
