Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2020 |
Roland Garros, Qualification ATP
|
1/32 | Renzo Olivo |
6-7
2-6 |
| 2020 |
Prostejov
|
1/16 | Jozef Kovalik |
7-6
6-2 |
| 2020 |
Ostrava
|
1/16 | Lukas Rosol |
2-6
6-4 6-0 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Yannick Hanfmann |
5-7
2-6 |
| 2021 |
Mexican Open
|
1/16 | Laslo Djere |
2-6
3-6 |
