Isner lost his fourth-round match to Roberto Bautista Agut in Miami on Tuesday.
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2017 |
Australian Open
|
1/64 | Steve Johnson |
3-6
4-6 4-6 |
| 2016 |
Cincinnati Masters
United States, Ohio, Cincinnati |
1/32 | Steve Johnson |
6-4
7-5 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Monte Carlo Masters
|
1/32 | Federico Delbonis |
7-5
6-1 |
| 2021 |
Monte Carlo Masters, Qualification
|
1/7 (Special Qual) | Federico Delbonis |
6-3
3-6 4-6 |
| 2021 |
Monte Carlo Masters, Qualification
|
1/14 (Special Qual) | Federico Delbonis |
2-6
5-7 |
| 2021 |
Andalucia Open
|
1/8 | Norbert Gombos |
5-7
7-6 7-6 |
| 2021 |
Andalucia Open
|
1/16 | Federico Delbonis |
5-7
1-6 |
| year | Event | RND | Winner | Results |
|---|---|---|---|---|
| 2021 |
Miami Open
|
1/64 | Yannick Hanfmann |
5-7
2-6 |
| 2021 |
Mexican Open
|
1/16 | Laslo Djere |
2-6
3-6 |
