Defending champion Agnieszka Radwanska has pulled out of next week's Brussels Open due to a shoulder injury. Radwanska says she is concerned about her shoulder holding up for Roland Garros and Wimbledon.

"It's been a while since I suffered from the shoulder injury and the pain has only worsened since the start of the clay season," Radwanska said in a statement. "Moreover, I am worried about Roland Garros and the grass-court season."

The fourth-ranked Radwanska was runner-up to Serena Williams in the 2012 Wimbledon final.