Meanwhile, Daria Kasatkina returns to the Top 10—and even sets a new career-high—after winning San Jose.

Karatsev is 8-19 in his last 27 matches and now faces Ymer, who is brimming with confidence after a win over Andy Murray.

No longer tennis betting's best kept secret, Brooksby is in a favorable spot on Tuesday against the Winston-Salem runner-up.

Insane tweeners and unbelievable around-the-net trick shots dominated the men's list.

"I'm ready physically, mentally, emotionally to go deep in the tournament. Hopefully I can have another successful year here in Paris," the world No. 1 said.

Despite the straight-set loss, the 22-year-old brought down the sparsely populated house with an incredible winner.

The world No. 1's only two first-round losses at majors came at his most beloved major.

Stan Wawrinka also survived in five sets, setting up a third-rounder against John Isner. Karen Khachanov joined the two by outlasting Mikael Ymer in four hours and 34 minutes.