With Carlos Alcaraz and Alexander Zverev also in the top half, can 2021 runner-up Stefanos Tsitsipas capitalize on his softer side of the draw?

The Greek has been stopped by both competitors during a clay season that has seen him successfully defend his Monte Carlo crown, add a runner-up effort in Rome and semifinal showing at Madrid.

Will this become the most impactful and significant French Open in recent memory? Taking stock of the top storylines heading into the second major of the season.

Novak Djokovic said he feels “fresh” and “sharp” after winning his first title of 2022 in Rome and putting his season’s rocky start behind him. Will it be enough to catapult him to an even bigger win in Paris?

The world No. 1 has now conquered the Italian capital six times in 2008, 2011, 2014, 2015, 2020 and 2022.

Ever hear the notion that metabolism is destiny? For a case study, check out the Greek’s win over Zverev in the semifinals of the Internazionali BNL d’Italia.

Tsitsipas beat up on Sinner when the two met at the Australian Open, but the Italian should be ready to compete in front of what will be a raucous home crowd.

Just as Zverev, Tsitsipas and rest of the Next Gen seemed to be consolidating their hold on the ATP's future, the 19-year-old's rapid rise effectively relegated that group to the shadows.

Feel old yet? Sounds like the Roland Garros runner-up does after watching Alcaraz romp to his second Masters victory in Madrid.

Or, will someone else emerge victorious to gain match momentum heading into Roland Garros?